Method of evaluating metabolism of the eye

A - Human Necessities – 61 – B

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A61B 3/12 (2006.01) A61B 3/14 (2006.01)

Patent

CA 2555782

A method and apparatus for measuring the retinal auto-fluorescence of a subject retina includes an excitation light source for providing an excitation light at a wavelength of at least 450nm and an image capture device for recording an ocular auto-fluorescence signal generated in response to the excitation light. The image capture device includes a filter for reducing background non-signal wavelengths from the ocular auto-fluorescence signal and an image intensifier for increasing the ocular auto-fluorescence signal strength. The method and apparatus may further include a processor that analyzes the auto-fluorescence signal to determine a contrast change or pattern to thereby detect retinal disease or damage. The processor may compare the images with control images, past images of the same eye or other diagnostic modalities such as fundus photography, angiography, or visual field testing to detect the retinal disease or damage.

L'invention concerne un procédé et un appareil permettant de mesurer l'autofluorescence rétinienne de la rétine d'un sujet, qui comprend une source lumineuse d'excitation à une longueur d'onde d'au moins 450 nm et un dispositif de capture d'image permettant d'enregistrer un signal oculaire autofluorescent produit en réponse à la lumière d'excitation. Ledit dispositif de capture d'image comprend un filtre permettant de réduire les longueurs d'onde d'arrière de plan de non-signal provenant du signal oculaire autofluorescent, et un intensificateur d'image permettant d'augmenter l'intensité du signal oculaire autofluorescent. Le procédé et l'appareil permettent également de mettre en oeuvre un processeur qui analyse le signal oculaire autofluorescent afin de déterminer un changement de contraste ou de motif, ce qui permet de détecter une maladie ou un dommage rétinien. Ledit processeur permet de comparer des images avec des images témoin, des images antérieures du même oeil ou d'autres modalités de diagnostic, telles que photographie de fond d'oeil, angiographie, ou test de champ visuel afin de détecter une maladie ou un dommage rétinien.

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