Method of evaluating the efficacy of drug on brain nerve cells

Details Method of evaluating the efficacy of drug on brain nerve cells Method of evaluating the efficacy of drug on brain nerve cells

A - Human Necessities

61

B

A61B 5/055 (2006.01) G01R 33/483 (2006.01)

Patent

CA 2254952

The present invention relates to a method to measure in vivo the effect of a drug on the function of the nerve cells of the brain of a patient suffering from a neurological disease, which comprises the steps of: a) measuring NAA signal intensity using MRS of the brain of the patient; b) subjecting the patient to a treatment with the drug to be tested and measuring NAA signal intensity using MRS of the brain of the patient; and c) comparing the spectra of steps a) and b) to determine whether the drug has an effect on the function of the nerve cells of the brain; whereby the increase in the NAA signal of step b) is indicative of a drug with a positive effect.

L'invention se rapporte à un procédé de mesure in vivo de l'effet d'un médicament sur le fonctionnement des neurones du cerveau d'un patient souffrant d'une maladie neurologique. Le procédé consiste: a) à mesurer l'intensité du signal NAA par spectroscopie par résonance magnétique (MRS) du cerveau du patient, b) à traiter le patient avec le médicament à tester et à mesurer l'intensité du signal NAA par MRS du cerveau du patient, et c) à comparer le spectre obtenu en a) au spectre obtenu en b) pour déterminer si le médicament a un effet sur le fonctionnement des neurones du cerveau. L'intensification du signal NAA en b) indique que le médicament a un effet positif.

Affiliated with

Also associated with

Rating

Method of evaluating the efficacy of drug on brain nerve cells does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of evaluating the efficacy of drug on brain nerve cells, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of evaluating the efficacy of drug on brain nerve cells will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1663494