G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/564 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2556557
The invention relates to a method of evaluating the therapeutic potential of a vaccination program comprising a vaccine for mucosal administration comprising one or more antigens and a vaccination protocol, the method comprising a) subjecting at least one test individual to the vaccination program, b) measuring the level of a biomarker antibody selected from the group consisting of IgA, IgG, IgE and IgX specific to the antigen in a biological sample from the test individual, and c) using the measurements obtained to evaluate the therapeutic potential of the vaccination program.
L'invention concerne un procédé pour évaluer le potentiel thérapeutique d'un programme de vaccination incluant un vaccin à administration mucosale comportant un ou plusieurs antigènes ainsi qu'un protocole de vaccination, ledit procédé consistant a) à soumettre au moins un individu d'essai au programme de vaccination, b) à mesurer le niveau d'un anticorps biomarqueur sélectionné dans le groupe constitué par IgA, IgG, IgE et IgX spécifique à l'antigène dans un échantillon biologique de l'individu d'essai et c) à utiliser les mesures obtenues pour évaluer le potentiel thérapeutique du programme de vaccination.
Ipsen Hans-Henrik
Jacobi Henrik Hugo
Lund Maerkedahl Lise
Alk Abello A/s
Ridout & Maybee Llp
LandOfFree
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