Method of examining cancer by assaying autoantibody against...

Details Method of examining cancer by assaying autoantibody against... Method of examining cancer by assaying autoantibody against...

G - Physics

01

N

G01N 33/574 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2405448

A novel method of examining cancer by assaying an autoantibody against MDM2 in the blood and a reagent and a kit therefor. For example, cancer is examined by an immunological method with the use of a peptide fragment of MDM2 as an antigen and anti-MDM2 antibody, which is optionally labeled, obtained from this antigen as an antibody for assaying the autoantibody as described above.

Cette invention, qui a trait à une nouvelle technique d'investigation du cancer faisant appel à une épreuve biologique d'un autoanticorps contre MDM2 dans le sang, concerne également un réactif ainsi qu'un nécessaire à cet effet. On procède, notamment, à une recherche de cancer par voie immunologique, dans le cadre de laquelle on utilise un fragment peptidique de MDM2 en tant qu'antigène ainsi qu'un anticorps anti MDM2, lequel est éventuellement marqué, obtenu à partir de cet antigène comme anticorps et ce, pour soumettre l'autoanticorps susmentionné à une épreuve biologique.

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