Method of forming an improved hydrophilic coating on a...

C - Chemistry – Metallurgy – 08 – J

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C08J 7/04 (2006.01) A61L 29/00 (2006.01) A61L 29/08 (2006.01) A61L 29/14 (2006.01) A61L 31/00 (2006.01) B32B 33/00 (2006.01) C08J 7/12 (2006.01)

Patent

CA 1292649

ABSTRACT A method of forming an improved hydrophilic coating by applying a non-reactive hydrophilic polymer surface layer with an osmolality in- creasing compound to produce a more stable hydrophilic surface and to produce a more slippery surface in wet condition. The polymer surface layer is treated with a solution having above 2% (weight-to-volume) of an osmolality increasing compound and then the solvent of the solution is evaporated. Osmolality increasing compounds are nontoxic organic or inorganic salts other than trihalogenids, mono- or di- saccharides or sugar alcohols. Preferred compounds are glucose, sorbitol, sodium chloride, sodium citrate, sodium bensoate, calcium chloride, potassium chloride, potassium iodide, potassium nitrate. The solution of the osmolality increasing compound contains preferably a polymer. Medical articles treated with the solution of osmolality in- creasing compounds according to the method above also relate to the invention.

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