G - Physics – 01 – N
Patent
G - Physics
01
N
324/1
G01N 24/08 (2006.01) G01R 33/54 (2006.01) G01R 33/56 (2006.01) G01R 33/561 (2006.01)
Patent
CA 1256492
ABSTRACT OF THE DISCLOSURE A method of high-speed magnetic resonance imaging in which the object to be imaged is placed in a high static magnetic field. Nuclear spins are excited in an image area in a selected plane of the object by superimposing a slice- selection gradient along an axis and applying a pulse of radio frequency magnetic field. Following an encoding pulse sequence and rephasing of the nuclear spins by the application of a 180° radio frequency pulse, mutually orthogonal phase-encoding and readout gradients are alternately applied in the image plane to effect a traversal through spatial frequency domain (k-space). In a preferred embodiment of the invention, the readout gradient is applied as a continuous sinusoidal wave. If phase errors vary slowly in time, only a partial k-space trajectory is required. In one variant of partial k-space imaging, the trajectory extends over the k-space origin, and the information acquired from the extension is used to compensate for any phase errors. If the same number of points are collected as in a full k-space acquisition, signal bandwidth is maintained, and spatial frequency response is increased. In a another variant, two or more partial k-space acquisitions are performed and then pieced together in a "mosaic" prior to Fourier transformation. In a further variant, partial k- space acquisitions in the direction of the readout gradient are combined with interleaved acquisitions in the direction of the phase-encoding gradient to avoid discontinuities. Chemical shift is eliminated either by the application of a suppression pulse of RF field or by tailoring the frequency spectrum of the rephasing pulse so as to preclude rephasing of one or other of the chemical moieties.
553393
Advanced Nmr Systems Inc.
Borden Ladner Gervais Llp
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