Method of identifying a polymorphism in cyp2d6

Details Method of identifying a polymorphism in cyp2d6 Method of identifying a polymorphism in cyp2d6

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2449752

The present invention relates to methods of detecting a polymorphism in a gene encoding xenobiotic metabolizing enzyme CYP2D6. The methodology disclosed is robust and can detect the presence of the wildtype and polymorphic sequences in the presence of gene duplication and gene conversion events.

La présente invention concerne des méthodes de détection d'un polymorphisme dans un gène codant une enzyme de métabolisation xénobiotique, CYP2D6. La méthode de l'invention est robuste et peut détecter la présence des séquences du type sauvage ou polymorphiques dans le cas d'événements de duplication génique ou de conversion génique.

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