Method of identifying and developing drug leads

Details Method of identifying and developing drug leads Method of identifying and developing drug leads

G - Physics

01

N

G01N 33/68 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2298629

A protein of interest is characterized by reactivity and/or aptamer descriptors as similar to a database protein, whose activity is mediated by a known drug. The search for drugs which mediate the protein of interest emphasizes compounds similar in structure to those which mediate the activity of the higher-scoring database proteins.

L'invention concerne une protéine d'intérêt caractérisée par une réactivité et/ou des descripteurs aptamères comme étant similaire à une protéine d'une base de données, dont l'activité est induite par un médicament connu. La recherche de médicaments induisant la protéine d'intérêt fait apparaître des composés similaires par leur structure à ceux qui induisent l'activité des protéines de la base de données à score plus élevé.

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