C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2555965
The invention relates to a method of identifying candidate genes that are potentially useful in the diagnosis and treatment of disease and/or inducement of hybrid vigour. In particular, the present invention relates to a method for identifying candidate genes capable of producing hybrid vigour or hybrid debility in an animal or plant, comprising the steps of: (i) comparing the nucleotide sequence of alleles of candidate genes; (ii) identifying nucleotide sequence differences in the alleles from said animal or plant; and (iii) identifying that the amino acid sequence variation between alleles of the candidate gene are located within two or more different exons within the candidate gene.
L'invention concerne un procédé pour identifier les gènes candidats qui sont potentiellement utiles dans le diagnostic ou le traitement des maladies et/ou dans l'activation de la vigueur hybrides. L'invention concerne notamment un procédé pour identifier les gènes candidats pouvant assurer la vigueur ou la débilité des hybrides chez un animal ou un végétal, et comprend les stades suivants: (i) comparer la séquence nucléotidique d'allèles de gènes candidats; (ii) identifier les différences de la séquence nucléotidique dans les allèles de l'animal ou du végétal; et (iii) identifier la variation des séquences d'acides aminés entre les allèles du gène candidat qui se trouvent dans deux ou plusieurs exons différents dans le gène candidat.
Hybrid Biosciences Pty Ltd
Sim & Mcburney
LandOfFree
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