Method of identifying ginko biloba in a plant extract by...

Details Method of identifying ginko biloba in a plant extract by... Method of identifying ginko biloba in a plant extract by...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12Q 1/00 (2006.01) A01H 5/00 (2006.01) C12N 5/04 (2006.01) C12N 15/29 (2006.01)

Patent

CA 2403303

The present invention is directed to a method of establishing an "identity" of Ginkgo biloba leaves or isolated ginkgolide B (GKB) or another component of the extract of Ginkgo biloba leaves, by obtaining a "gene regulation profile". The invention is also directed to a method of verifying the identity of a Ginkgo biloba extract by comparing the gene regulation profile of a Gingko biloba extract of unknown or questionable origin with the gene regulation pofile of a Gingko biloba extract of known origin. The present invention is further directed to a method of establishing a gene expression profile of Ginkgolide A, Ginkgolide B or any other component isolated from a Ginkgo biloba extract, more particularly, from EGB 761®.

L'invention concerne un procédé permettant d'établir une <= identé >= de feuilles de Ginkgo biloba ou d'un ginkgolide B isolé (GKB), ou d'un autre composant de l'extrait des feuilles de Ginkgo biloba, par obtention d'un <= profil de régulation génique >=. L'invention concerne également un procédé permettant de vérifier l'identité de l'extrait de Ginkgo biloba en comparant le profil de régulation génique d'un extrait de Gingko biloba d'origine inconnue ou discutable avec le profil de régulation génique d'un extrait de Gingko biloba d'orgine connue. L'invention concerne en outre un procédé permettant d'établir un profil d'expression génique de Gingkolide A, de Gingkolide B ou de tout autre composant isolé d'un extrait de Gingko biloba, et plus particulièrement de EGB 761 ?.

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