Method of identifying hairpin dna probes by partial fold...

C - Chemistry – Metallurgy – 07 – H

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C07H 21/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) C40B 30/02 (2006.01) G01N 33/50 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2551842

Method of identifying molecular beacons in which a secondary structure prediction algorithm is employed to identify oligonucleotide sequences within a target gene having the requisite hairpin structure. Isolated oligonucleotides, molecular beacons prepared from those oligonucleotides, and their use are also disclosed.

Procédé d'identification de phares moléculaires dans lequel on emploie un algorithme de prédiction de structure secondaire pour identifier des séquences d'oligonucléotides à l'intérieur d'un gène cible ayant la structure en épingle à cheveux requise. Il est également exposé des oligonucléotides isolés, des phares moléculaires préparés à partir de ces oligonucléotides et leur utilisation.

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