Method of identifying properties of substance with respect...

G - Physics – 01 – N

Patent

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Details

G01N 33/566 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) G01N 33/88 (2006.01)

Patent

CA 2383135

An object of the present invention is to provide a method of identifying a substance which acts on a newly found second human prostaglandin D2 receptor subtype that differs from the DP receptor, and is useful for treating or preventing various diseases. In order to attain the object, the present invention provides a method of identifying properties of a test substance with respect to a human prostaglandin D receptor, by establishing correlation between the effect of a test substance on human CRTH2 with the effect of the test substance on the human prostaglandin D receptor.

L'invention concerne une technique permettant de déterminer les propriétés d'une substance agissant sur un nouveau second sous-type de récepteur humain de prostaglandine D2, différent du récepteur DP, utile dans le traitement ou la prévention de nombreuses maladies. Cette technique consiste à examiner l'effet de la substance d'essai sur le récepteur humain de prostaglandine D en corrélation avec ses effets sur le CRTH2 humain, et ce afin d'identifier les propriétés de ladite substance sur les récepteurs humains de prostaglandine D.

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