Method of identifying toxic agents using differential gene...

Details Method of identifying toxic agents using differential gene... Method of identifying toxic agents using differential gene...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/70 (2006.01)

Patent

CA 2369969

Disclosed are methods of identifying toxic agents, e.g., hepatotoxic agents, using differential gene expression. Also disclosed are novel nucleic acid sequences whose expression is differentially regulated by troglitazone.

L'invention concerne des procédés d'identification d'agents toxiques, tels que des agents hépatotoxiques, au moyen d'une expression génétique différentielle. L'invention concerne également des nouvelles séquences d'acide nucléique dont l'expression est régulée de manière différentielle par de la troglitazone.

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