Method of immunisation against the four serotypes of dengue

A - Human Necessities – 61 – K

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A61K 39/12 (2006.01) C12N 7/00 (2006.01)

Patent

CA 2656349

The invention relates to a method of inducing homologous protection against the four serotypes of dengue in a patient, comprising the sequential administration in said patient (i) of a dose of a vaccinal virus of the dengue of a first serotype and a dose of a vaccinal virus of a second serotype, and (ii) a dose of a vaccinal virus of the dengue of a third serotype and a dose of a vaccinal virus of the dengue of a fourth serotype, in which the vaccinal viruses of the dengue (ii) are administered at least 30 days and no more than 1 year after the administration of the vaccinal viruses (i).

L'invention concerne une méthode pour induire une protection homologue contre les 4 sérotypes de la dengue chez un patient, comprenant l'administration séquentielle audit patient (i) d'une dose d'un virus vaccinal de la dengue d'un premier sérotype et d'une dose d'un virus vaccinal de la dengue d'un deuxième sérotype, et (ii) d'une dose d'un virus vaccinal de la dengue d'un troisième sérotype et d'une dose d'un virus vaccinal de la dengue d'un quatrième sérotype, dans laquelle les virus vaccinaux de la dengue (ii) sont administrés au moins 30 jours et au plus 1 ans après administration des virus vaccinaux (i).

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