Method of improving the yield of heterologous protein...

C - Chemistry – Metallurgy – 12 – P

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195/48, 195/1.29

C12P 21/02 (2006.01) C07K 14/52 (2006.01) C12N 1/38 (2006.01) C12N 15/00 (2006.01)

Patent

CA 1262694

Abstract of the Disclosure A method for improving the yield of heterologous protein such as IFN-.alpha. IFN-.beta., and IL-2, produced by recombinant bacteria involves supplementing the nutrient medium in which the bacteria are grown with ethanol and/or amino acid mixture during the terminal phase of the cultivation.

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