Method of inactivating incompatibility-reaction- causing...

A - Human Necessities – 61 – K

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167/46

A61K 49/00 (2006.01) A61K 35/16 (2006.01) C07K 16/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1248447

ABSTRACT OF THE DISCLOSURE A method for determining incompatibility-reaction- causing vasoactive, leucopenic, or bronchospastic substances in therapeutically and prophylactically applicable blood products, wherein the blood products are intraarterially injected into a test animal, characterized in that for vasoactive and leucopenic substances the test animal is dog, and either or both of blood pressure decrease or decrease in the number of leucocytes is determined, and that for bronchospastic substances the test animal is guinea pig, and an increase in respiratory pressure is determined.

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