A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 33/00 (2006.01) A61F 2/06 (2006.01) A61K 38/18 (2006.01) A61K 38/21 (2006.01) A61K 38/58 (2006.01) A61K 39/395 (2006.01) A61K 47/30 (2006.01) A61L 27/00 (2006.01) A61L 29/00 (2006.01) A61L 31/10 (2006.01) A61L 31/14 (2006.01) A61L 31/16 (2006.01) A61M 37/00 (2006.01) A61M 25/00 (2006.01)
Patent
CA 2172187
The drug-loaded polymeric material containing a therapeutic drug can be applied to a structure of an intravascular stent. A therapeutically effective amount of a therapeutic drug is incorporated into such a layer of polymeric material, without significantly increasing the thickness of the stent, to avoid interfering with the function of the stent. The drug- loaded polymer coating of the stent can formed to include pores, can be multi-layered to permit the combination of a plurality of different drug containing materials in a single stent, and can include a rate controlling membrane to allow for controlled retention and delivery of selected drugs within the affected blood vessel upon implantation. The layer of polymeric material is manufactured by combining the selected polymeric material with a relatively high loading of the therapeutic drug in a thermal process, such as coextrusion of the therapeutic drug with the polymeric material. The therapeutic drug is dispersed and incorporated into the polymer as small particles, preferably having a maximum cross-sectional dimension of 10 microns.
Eury Robert P.
Garguilo Darlene
Villareal Plaridel
Advanced Cardiovascular Systems Inc.
Smart & Biggar
LandOfFree
Method of incorporating drugs into a polymer component of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of incorporating drugs into a polymer component of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of incorporating drugs into a polymer component of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1848019