Method of increasing oral absorption of .beta.-lactam...

A - Human Necessities – 61 – K

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167/162, 167/187

A61K 31/43 (2006.01) A61K 31/545 (2006.01) A61K 47/00 (2006.01)

Patent

CA 1165690

ABSTRACT OF THE DISCLOSURE: A method and drug form are provided for increas- ing the oral absorption of .beta.-lactam antibiotics such as the penicillins, cephalosporins and related chemical species by the oral aaministration of said .beta.-lactam anti- biotics in a suitable pharmaceutically accepted excipient to which has been added a hydroxy aryl or hydroxy aralkyl acid or salt, amide or ester thereof. The hydroxyaryl or hydroxyaralkyl acid or salt, amide or ester thereof is present in the drug form in quantities sufficient to be effective in enhancing the rate of oral absorption of the .beta.-lactam antibiotic.

372411

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