Method of increasing oral absorption of polar bioactive agents

Details Method of increasing oral absorption of polar bioactive agents Method of increasing oral absorption of polar bioactive agents

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Patent

CA 1165689

Rx82A METHOD OF INCREASING ORAL ABSORPTION OF POLAR BIOACTIVE AGENTS ABSTRACT OF THE DISCLOSURE A method and drug form are provided for increasing the oral absorption of polar bioactive agents such as xanthines, polyhydroxylic substances, zwitterions; polypeptides and organic anions and related chemical species by the oral administration of said polar bioactive agents in a suitable pharmaceutically accepted excipient to which has been added a hydroxyaromatic, hydroxyaryl or hydroxy aralkyl acid or salt amide or ester thereof. The hydroxy aryl or hydroxy aralkyl acid or salt amide or ester thereof is present in the drug form in quantities sufficient to be effective in enhancing the rate of oral absorption of the polar bioactive agents.

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