Method of increasing the in vivo recovery of therapeutic...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 19/00 (2006.01) A61K 47/48 (2006.01) C12N 9/64 (2006.01) C07K 14/755 (2006.01) C12N 15/00 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2649199

The present invention relates to the field of modified therapeutic polypeptides with increased in vivo recovery compared to their non-modified parent polypeptide. I.e., the invention relates to fusions of therapeutic polypeptides with recovery enhancing polypeptides connected directly or optionally connected by a linker peptide.

La présente invention concerne des polypeptides thérapeutiques modifiés présentant un taux de récupération in vivo accru par comparaison avec leur polypeptide parent non modifié. Plus particulièrement, l'invention concerne la fusion de polypeptides thérapeutiques avec des polypeptides augmentant le taux de récupération reliés directement ou éventuellement reliés par un peptide de liaison.

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