Method of increasing working time ttcp

A - Human Necessities – 61 – K

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Details

A61K 6/06 (2006.01) A61L 24/00 (2006.01) A61L 24/02 (2006.01) A61L 27/12 (2006.01) C04B 12/02 (2006.01) C04B 28/34 (2006.01)

Patent

CA 2555240

A tetracalcium phosphate (TTCP) particle for use in preparing a fast-setting, bioresorbable calcium phosphate cement is disclosed. The TTCP particle has a basic calcium phosphate whiskers on a surface thereof; the basic calcium phosphate whiskers having a Ca/P molar ratio greater than 1.33, and having a length up to about 5000 nm and a width up to about 500 nm. The basic calcium phosphate whiskers are substantially free of a hydroxyapatite phase and mainly composed of TTCP phase.

L'invention concerne une particule de phosphate tétracalcique (TTCP) permettant la préparation d'un ciment de phosphate de calcium biorésorbable à prise rapide. Cette particule de TTCP comporte des barbes de phosphate de calcium basiques à sa surface, ces barbes de phosphate de calcium présentant un rapport molaire Ca/P supérieur à 1,33, et une longueur maximale d'env. 5000 nm et une largeur maximale d'env. 500 nm. Les barbes de phosphate de calcium sont sensiblement exempte d'une phase hydroxyapatite, et se composent principalement d'une phase de TTCP.

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