Method of indentifying and modulating the activity of label...

Details Method of indentifying and modulating the activity of label... Method of indentifying and modulating the activity of label...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01) G01N 33/58 (2006.01) A61K 49/02 (1990.01)

Patent

CA 2106862

2106862 9217779 PCTABS00016 Methods of detecting label retaining cells in self-renewing tissues, such as hair follicle, are provided. Methods of modulating the activity of slow-cycling cells and methods of evaluating the efficacy of agents for modulating the activity of stem cell populations are also provided. Generally, cells are continuously labeled, induced into a proliferative phase by exposure to an agent such as TPA or a cytokine, and then observed in relation to established criteria.

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