Method of inducing immunity against stratum corneum...

Details Method of inducing immunity against stratum corneum... Method of inducing immunity against stratum corneum...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 38/48 (2006.01) A61K 39/395 (2006.01) C07H 21/04 (2006.01) C07K 1/00 (2006.01) C12Q 1/37 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2564126

The present invention discloses the protease stratum corneum chymotrytic enzyme (SCCE) is specifically over-expressed in ovarian and other malignancies. A number of SCCE peptides can induce immune responses to SCCE, thereby demonstrating the potential of these peptides in monitoring and the development of immunotherapies for ovarian and other malignancies.

La présente invention décrit l~enzyme chymotryptique de la couche cornée (SCCE, Stratum Corneum Chymotrytic Enzyme) protéase, qui est particulièrement surexprimée dans les malignités ovariennes et autres. Une quantité de peptides SCCE peut provoquer des réactions immunitaires aux SCCE, démontrant ainsi le potentiel de ces peptides dans la surveillance et le développement d~immunothérapies pour les malignités ovariennes et autres.

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