Method of inducing or modulating immune response

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/18 (2006.01) A61P 37/02 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2560055

The use of axotrophin, also known as MARCH VII to induce or regulate immune response to an antigen whether foreign or self, suitably in a vertebrate, for example a mammal is disclosed. Isolated axotrophin and nucleotides and polypeptides encoded by or derived from axotrophin, compositions containing one or more thereof and assay methods are provided as further aspects of the invention.

La présente invention se rapporte à l'utilisation d'axotrophine, également connue sous le nom MARCH VII, pour induire ou réguler une réponse immunitaire contre un antigène qu'il soit exogène ou endogène, chez un vertébré, tel que par exemple un mammifère. Cette invention concerne également de l'axotrophine isolée et des nucléotides et des polypeptides codés par l'axotrophine ou des dérivés de cette dernière, des compositions contenant un ou plusieurs de ces derniers ainsi que des méthodes de dosage.

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