Method of inducing vasodilation and treating pulmonary...

Details Method of inducing vasodilation and treating pulmonary... Method of inducing vasodilation and treating pulmonary...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/70 (2006.01) C12N 9/02 (2006.01)

Patent

CA 2260771

This invention relates to a gene therapy method for inducing pulmonary vasodilation. More specifically, this invention involves introducing the nitric oxide synthase gene into lungs resulting in pulmonary vasodilation. This results in a hypotensive effect in the pulmonary circulation which does not significantly affect systemic blood pressure or cardiac index. This method is useful to treat primary pulmonary hypertension or pulmonary hypertension secondary to various disease states.

L'invention concerne un procédé de thérapie génique servant à provoquer la vasodilatation pulmonaire. Elle consiste, plus spécifiquement, à introduire le gène de synthase d'oxyde nitrique dans les poumons, ce qui provoque la vasodilatation pulmonaire. Ceci exerce un effet d'hypotension sur la circulation pulmonaire et n'affecte pratiquement pas la pression sanguine systémique ni l'indice cardiaque. Ce procédé est utile pour traiter l'hypertension pulmonaire primaire ou consécutive à différentes maladies.

Affiliated with

Also associated with

Rating

Method of inducing vasodilation and treating pulmonary... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of inducing vasodilation and treating pulmonary..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of inducing vasodilation and treating pulmonary... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2045523