Method of inhibiting angiogenesis by using ephrin b2

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01) A61P 9/00 (2006.01) A61P 15/00 (2006.01) A61P 17/14 (2006.01) A61P 19/02 (2006.01) A61P 27/02 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C12N 5/00 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2623563

It is intended to provide a method of inhibiting angiogenesis or neoangiogenesis and a composition therefor, and a method which is useful in treating a disease or a disorder relating to angiogenesis or neoangiogenesis and a composition therefor. The above-described compositions contain an effective amount of Ephrin B2 and the above-described methods involve the step of administering an effective amount of Ephrin B2. These compositions and methods are useful in treating a disease or a disorder relating to angiogenesis or neoangiogenesis. Moreover, these compositions and methods can inhibit neoangiogenesis from the retina.

La présente invention concerne un procédé d~inhibition de l'angiogenèse ou de la néoangiogenèse et une composition pour ledit procédé, ainsi qu'un procédé permettant de traiter une maladie ou un trouble lié à l~angiogenèse ou à la néoangiogenèse et une composition pour ledit procédé. Les compositions décrites ci-dessus contiennent une quantité efficace d~éphrine B2 et les procédés décrits ci-dessus impliquent l~étape consistant à administrer une quantité efficace d'éphrine B2. Ces compositions et procédés sont utilisés dans le traitement d'une maladie ou d'un trouble lié à l'angiogenèse ou à la néoangiogenèse. De plus, ces compositions et procédés peuvent inhiber la néoangiogenèse de la rétine.

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