A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4439 (2006.01) A61P 35/00 (2006.01) C07D 401/10 (2006.01)
Patent
CA 2649755
A method of reducing or inhibiting kinase activity of C KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C KIT using a ompound of the present invention: Formula (I), or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof. The present invention is further directed to methods for treating conditions such as cancers and other cell proliferative disorders.
L'invention concerne un procédé permettant de réduire ou inhiber l'activité de kinase de C KIT dans une cellule ou chez un sujet, ainsi que l'utilisation de ces composés chez un sujet pour prévenir ou traiter un trouble cellulaire prolifératif et/ou des troubles liés à C KIT en utilisant un composé de la présente invention : formule (I), ou un solvate, un hydrate, un tautomère ou un sel pharmaceutiquement acceptable de ce composé. La présente invention concerne en outre des procédés de traitement d'affections telles que des cancers et d'autres troubles cellulaires prolifératifs.
Ballentine Shelley K.
Chen Jingsheng
Desjarlais Renee L.
Illig Carl R.
Manthey Carl L.
Janssen Pharmaceutica N.v.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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