Method of inhibiting fibrosis

Details Method of inhibiting fibrosis Method of inhibiting fibrosis

A - Human Necessities

61

K

A61K 31/165 (2006.01) A61K 31/16 (2006.01) A61K 31/175 (2006.01)

Patent

CA 2107371

2107371 9217065 PCTABS00016 Disclosed is a method of inhibiting fibrosis in a human or animal subject afflicted with a fibrosing disorder. The method comprises administering to the subject an effective fibrosis-inhibiting amount of a compound of formula (I), wherein: n is 1 or 2, R is selected from the group consisting of hydrogen, C1-C4 alkyl, hydroxy, amino, and nitro; and R' is selected from the group consisting of hydrogen and C1-C4 alkyl, or a pharmaceutically acceptable salt thereof. Preferred as a compound of formula (I) is benzoic hydrazide. Pharmaceutical formulations and the use of compounds of formula (I) for making the same are also disclosed.

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