Method of inhibiting osteoclast activity

Details Method of inhibiting osteoclast activity Method of inhibiting osteoclast activity

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2328140

Isolated soluble RANK receptors, DNAs encoding such receptors, and pharmaceutical compositions made therefrom, are disclosed. The isolated can be used to regulate osteoclastogenesis, and hence treat disease in which there is excess bone loss.

L'invention concerne des récepteurs RANK solubles isolés, des ADN codant ces récepteurs et des compositions pharmaceutiques préparées sur cette base. Les récepteurs isolés peuvent être utilisés pour réguler l'ostéoclastogenèse et, partant, pour traiter les maladies liées à une perte excessive de masse osseuse.

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