Method of inhibiting the activity of human immunodeficiency...

Details Method of inhibiting the activity of human immunodeficiency... Method of inhibiting the activity of human immunodeficiency...

A - Human Necessities

61

K

167/179

A61K 31/00 (2006.01)

Patent

CA 2032748

A method for inhibiting the activity of human immunodeficiency virus (HIV) in vivo comprises administering to a human host an antimalarial drug, which is capable of exhibiting a protective effect, a curative effect, or of pre- venting transmission of malaria in humans. The antimalarial drug is selected from the group consisting of (a) alkaloids; (b) 9-amino-acridines; (c) 4-aminoquinolines; (d) 8-aminoquinolines; (e) biguanides; (f) dihyrofolate reductase inhibitors; (g) sulfones; (h) sulfonamides; (i) mefloquine; (j) halofantrine; (k) hydroxyanilino-benzo-naphtyridines; and (l) sesquiterpene lactones. The antimalarial drug is administered to the human in an amount sufficient to prevent or at least inhibit infection of T lymphocytes by HIV in vivo or to prevent or at least inhibit replication of HIV in vivo.

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