Method of inhibiting the transport of l-glutamate

Details Method of inhibiting the transport of l-glutamate Method of inhibiting the transport of l-glutamate

C - Chemistry, Metallurgy

07

D

C07D 207/16 (2006.01) A61K 31/40 (2006.01) A61K 31/675 (2006.01) C07F 9/572 (2006.01)

Patent

CA 2069912

2069912 9106536 PCTABS00005 A method of inhibiting the transport of a neurotransmitter away from the synapse comprising contacting a neurotransmitter transporter with a compound having structure (I), wherein R1 = CO2H; -P(OH2); -SO3H; CO2R3; P(OR3)2; -SO3R; (a); or CONHR3 in any combination and wherein R2 = OR3, NR32, alkyl, or substituted alkyl and R3 = alkyl or substituted alkyl.

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