A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2527621
A method of using tissue factor antagonists to treat proliferative diseases characterized by neovascularization such as cancer, rheumatoid arthritis, psoriasis, or proliferative retinopathy. or macular degeneration. Tissue factor antagonists capable of rapid prevention of blood clotting via the extrinsic pathway are also capable of inhibiting tumor growth in mammals.
La présente invention concerne un procédé pour l'utilisation d'antagonistes de facteurs tissulaires pour traiter des maladies proliférantes caractérisées par une néovascularisation, comme c'est le cas du cancer, de l'arthrite rhumatoïde, le psoriasis, la rétinopathie proliférante ou la dégénérescence maculaire. Des antagonistes capables d'une prévention rapide de la coagulation sanguine via le canal extrinsèque, sont également capables d'inhiber la croissance tumorale chez des mammifères.
Anderson Glenn M.
Nakada Marian
Ngo Cam
Tawadros Richard
Centocor Inc.
Centocor Ortho Biotech Inc.
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
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