Method of inhibiting viral reproduction

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/04 (2006.01) A61K 9/127 (2006.01) A61K 31/11 (2006.01) A61K 31/13 (2006.01) A61K 38/46 (2006.01) A61K 7/16 (1995.01) A61K 7/40 (1995.01)

Patent

CA 2153780

A new method of inactivating enveloped viruses and preparations useful in accomplishing this inactivation are disclosed. The method is based on the discovery that paucilamellar lipid vesicles, preferably having non-phospholipids as their primary structural material, can fuse with enveloped virus and that the nucleic acid of the virus denatures shortly after the fusion. The method is useful for inactivating viruses such as orthomyxoviruses, paramyxoviruses, coronaviruses, and retroviruses.

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