Method of intraoperatively detecting and locating tumoral...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/00 (2006.01) A61K 51/08 (2006.01) C07K 7/00 (2006.01) C07K 14/655 (2006.01) A61K 38/00 (2006.01) A61K 43/00 (1990.01) A61K 49/02 (1990.01)

Patent

CA 2131315

2131315 9318797 PCTABS00025 The invention relates to a method of intraoperatively detecting and locating tumoral tissues in the body of a warm-blooded living being, comprising (a) parenterally administering to said being a pharmaceutical composition comprising, in a quantity sufficient for detection by a gamma detecting probe, a peptide compound labelled with a low-energy gamma photon emitting radionuclide, and then (b), after allowing the active substance to be taken up in the tumoral tissues and after blood clearance of radioactivity, subjecting said being to a radioimmunodetection technique by using a gamma detecting probe. The invention further relates to a method of radioguided surgery.

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