Method of isolating cd8+ cells, and related hybridoma cells,...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/078 (2010.01) C07K 14/725 (2006.01) C07K 16/28 (2006.01) C12N 5/20 (2006.01) C12P 21/08 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2365639

This invention provides a method of isolating CD8+ cells which employs an antibody which specifically binds to CD8 molecules present on the surface of CD8+ cells but does not activate the CD8+ cells once bound. This invention also provides related hybridoma cell lines, monoclonal antibodies, antigenic polypeptides, isolated CD8+ cells, and kits.

Cette invention porte sur un procédé d'isolation des cellules CD8?+¿, ce procédé utilisant un anticorps qui se lie de manière spécifique aux molécules CD8 présentes sur la surface des cellules CD8?+¿, mais qui n'active pas les cellules CD8?+¿ une fois liées. Cette invention porte également sur des lignées cellulaires hybridomes, des anticorps monoclonaux, des polypeptides antigéniques, des cellules CD8?+¿ isolées et sur des kits.

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