C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/073 (2010.01) A61K 35/48 (2006.01)
Patent
CA 2529718
The present invention relates a method for isolating four cell types from a single umbilical cord as pure cultures. These cell lines (epithelial cells, fibroblasts, smooth muscle cells and endothelial cells) can be characterised and utilised in experimental models and for therapeutic purposes. Particularly, the umbilical cells isolated herein are used to form a tissue replacement or engineered living composition. Also, the isolated umbilical cells of the invention may have the potential of progenitor cells.
L'invention concerne une méthode permettant d'isoler quatre types de cellules d'un seul cordon ombilical sous forme de cultures pures. Ces lignées cellulaires (cellules épithéliales, fibroblastes, cellules des muscles lisses et cellules endothéliales) peuvent être caractérisées et utilisées dans des modèles expérimentaux et à des fins thérapeutiques. D'une manière plus spécifique, les cellules ombilicales isolées sont utilisées pour former un remplacement de tissu ou une composition vivante modifiée. Par ailleurs, les cellules ombilicales isolées selon l'invention peuvent présenter le potentiel de cellules progénitrices.
Auger Francois A.
Germain Lucie
Hayward Cindy J.
Remy-Zolghadri Murielle
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Universite Laval
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