Method of judging risk for drug-induced granulocytopenia

Details Method of judging risk for drug-induced granulocytopenia Method of judging risk for drug-induced granulocytopenia

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2530168

It is intended to provide a means of judging the risk for onset of drug- induced granulocytopenia in humans. A method of judging the risk for onset of drug-induced granulocytopenia which comprises detecting a gene polymorphism in human insulin receptor substrate-2 gene of a subject and using it as an indication in judging the risk for onset of drug-induced granulocytopenia.

L'invention concerne un moyen permettant de déterminer le risque d'un début de granulocytopénie induite par des médicaments chez l'homme. L'invention concerne plus spécifiquement un procédé permettant de déterminer le risque d'un début de granulocytopénie induite par des médicaments, lequel procédé consiste à détecter un polymorphisme génétique dans un gène 2 de substrat récepteur de l'insuline humain chez un sujet, et à l'utiliser en tant qu'indication pour déterminer le risque d'un début de granulocytopénie induite par des médicaments.

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