Method of large scale production of hepatitis a virus

Details Method of large scale production of hepatitis a virus Method of large scale production of hepatitis a virus

C - Chemistry, Metallurgy

12

N

C12N 7/02 (2006.01) A61K 39/29 (2006.01) C07K 14/10 (2006.01) C12N 5/00 (2006.01)

Patent

CA 2469589

The present invention provides methods of large scale production of Hepatitis A Virus (HAV) on VERO cells bound to microcarrier. The invention also provides for methods of isolation of HAV from the cell culture supernatant of HAV infected VERO cells.

L'invention concerne des procédés de production en série de virus de l'hépatite A (VHA) sur des lignées cellulaires VERO liées à un microsupport. L'invention concerne en outre des procédés d'isolation du VHA de surnageant de culture cellulaire de lignées cellulaires VERO infectées par le VHA.

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