Method of lessening the risk of vertebral fractures

A - Human Necessities – 61 – K

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A61K 31/66 (2006.01) A61K 31/06 (2006.01) A61K 31/44 (2006.01) A61K 31/663 (2006.01) A61P 19/10 (2006.01)

Patent

CA 2213076

Alendronate, a bisphosphonate, when administered daily over a substantial period of time, can reduce the rate of vertebral fractures in post-menopausal women. Further it can reduce the number and severity of fractures. Also, administration of alendronate can prevent spinal deformity, and loss in height.

Cette invention concerne un biphosphonate, plus précisément un alendronate, qui, lorsqu'il est administré quotidiennement pendant une période suffisamment longue, permet de diminuer le taux de fractures vertébrales chez les femmes en situation postménopausique. Cet alendronate peut également diminuer le nombre et la gravité des fractures. L'administration d'alendronate peut enfin prévenir les déformations spinales ainsi que l'amenuisement de la taille.

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