Method of lowering crp and reducing systemic inflammation

Details Method of lowering crp and reducing systemic inflammation Method of lowering crp and reducing systemic inflammation

A - Human Necessities

61

K

A61K 31/194 (2006.01) A61K 31/00 (2006.01) A61K 31/075 (2006.01) A61K 31/11 (2006.01) A61K 31/19 (2006.01) A61K 31/215 (2006.01) A61K 31/41 (2006.01) A61K 31/426 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61P 9/10 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2505915

Disclosed are methods of lowering plasma CRP levels, reducing systemic inflammation, and inhibiting proinlammatory cytokine induced CRP production by administering an effective amount of a substituted dialkyl ether, substituted alkyl, substituted aryl-alkyl, substituted dialkyl thioether, substituted dialkyl ketone, substituted-alkyl, or a pharmaceutically acceptable salt of the substituted dialkyl ether, substituted alkyl, substituted aryl-alkyl, substituted dialkyl thioether, substituted dialkyl ketone, or substituted- alkyl or a pharmaceutical composition comprising a substituted dialkyl ether, substituted alkyl, substituted aryl-alkyl, substituted dialkyl thioether, substituted dialkyl ketone, substituted-alkyl.

L'invention concerne des méthodes de diminution de niveaux de CRP du plasma, de réduction d'inflammation systémique et d'inhibition de production de CRP induites par les cytokines proinflammatoires par administration d'une quantité efficace d'un dialkyle éther substitué, d'un alkyle substitué, d'un aryle-alkyle substitué, d'un dialkyle thioéther substitué, d'une dialkyle cétone substituée, d'un alkyle substitué, ou d'un sel pharmaceutiquement acceptable du dialkyle éther substitué, de l'alkyle substitué, de l'aryle-alkyle substitué, du dialkyle thioéther substitué, de la dialkyle cétone substituée, ou de l'akyle substitué ou une composition pharmaceutique comprenant un dialkyle éther substitué, un alkyle substitué, un aryle-alkyle substitué, un dialkyle thioéther substitué, une dialkyle cétone substituée, un alkyle substitué.

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