Method of magnetic resonance investigation of a sample using...

G - Physics – 01 – R

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

G01R 33/48 (2006.01) A61B 5/055 (2006.01) A61K 49/06 (2006.01) A61K 49/10 (2006.01) G01R 33/563 (2006.01)

Patent

CA 2417724

The present invention provides a met hod of magnetic resonance investigation of a sample, preferably a human or non-human animal body, said method comprising: i) obtaining a MR imaging agent containing it its molecular structure at least one storage non-zero nuclear spin nuclei; ii) nuclear spin polarising said storage nucleic in said MR imaging agent; iii) administering the polarised MR imaging agent to said sample; iv) subjecting said sample to a pulse sequence which causes polarisation to be transferred from said storage nuclei to at lest one detection non-zero nuclear spin nuclei, wherein the gyromagnetic ratio of said detection nuclei is greater than that of said storage nuclei; v)exposing said sample to a radiation at a frequency selected to excite nuclear spin transitions in selected detection nuclei therein; vi) detecting magnetic resonance signals form said sample; and vii) optionally generating an image, dynamic flow data, diffusion data, perfusion data, physiological data or metabolic data from said detected signals.

La présente invention concerne un procédé d'investigation par résonance magnétique (IRM) d'un échantillon. Ce procédé consiste à (i) obtenir un agent d'imagerie par résonance magnétique contenant dans sa structure moléculaire au moins un noyau de stockage de spin nucléaire non nul ; (ii) un spin nucléaire polarisant lesdits noyaux de stockage dans ledit agent d'IRM ; (iii) administrer l'agent d'IRM polarisé audit échantillon ; (iv) soumettre ledit échantillon à une séquence d'impulsions qui amène la polarisation à être transférée dudit noyau de stockage à au moins un noyau de détection de spin nucléaire nul, selon lequel le rapport gyromagnétique dudit noyau de détection est supérieur à celui dudit noyau de stockage. Ce procédé consiste également à (v) exposer ledit échantillon à un rayonnement à une fréquence sélectionnée pour exciter les transitions de spin nucléaire dans des noyaux de détection sélectionnés et enfin (vi) détecter les signaux de résonance magnétique à partir dudit échantillon.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Method of magnetic resonance investigation of a sample using... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of magnetic resonance investigation of a sample using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of magnetic resonance investigation of a sample using... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1988698

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.