Method of making a tartar control dentifrice containing...

A - Human Necessities – 61 – K

Patent

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A61K 7/20 (1995.01) A61K 7/18 (1995.01)

Patent

CA 2221516

The present invention relates to a method of manufacturing predominately undissolved pyrophosphate and calcium peroxide compositions comprising the stepsof: (a) preparing a mixture of a soluble fluoride ion source and one or more aqueous carrier materials; (b) adding tetrasodium pyrophosphate and calcium peroxide, all at once or in portions, under conditions wherein less than about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture, and wherein anyfurther remaining aqueous carrier materials not added to the mixtures during step (a) are added in whole or in part in step (b) or thereafter, either by themselves or with any remaining amount of the tetrasodium pyrophosphate or calcium peroxide under conditions such that less then about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture; and (c) heating the mixture.

La présente invention concerne une méthode pour fabriquer des compositions de pyrophosphate et de peroxyde de calcium non dissoutes, de manière prédominante comprenant les étapes suivantes : a) préparer un mélange d'une source d'ion fluorure soluble et d'une ou de plusieurs matières transporteuses aqueuses; b) ajouter du pyrophosphate tétrasodique et du peroxyde de calcium, en même temps ou par fractions, dans des conditions telles que moins d'environ 20 % du pyrophosphate et du peroxyde de calcium total soient dissous dans le mélange, et que toutes les matières transporteuses aqueuses restantes non ajoutées au mélange durant l'étape a) soient ajoutées en entier ou par portion dans l'étape b) ou après, soit seules soit avec toute quantité restante de pyrophosphate tétrasodique ou de peroxyde de calcium dans des conditions telles que moins d'environ 20 % du pyrophosphate et du peroxyde de calcium total soient dissous dans le mélange; et c) chauffer le mélange.

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