Method of making collagen fibers for surgical use

Details Method of making collagen fibers for surgical use Method of making collagen fibers for surgical use

A - Human Necessities

61

L

8/54

A61L 17/00 (2006.01)

Patent

CA 1161209

Abstract of the disclosure A method is provided for the manufacture of collagen fibers for surgical purposes, in which Achilles tendons or hides from cottle are decomposed in an alkaline medium and are mechanically treated after treatment with an acid, deswelled, cross- linked and dried, wherein the Achilles tendons are decomposed in an alkaline medium to an amino-nitrogen content of from 0.15 to 0.30 µmoles/ g and after a hydro- chloric acid treatment and washing to a pH value of from 2 to 4, the swollen collagen substance is reduced in thickness under pressure forming a two-dimensional network, then the individual longitudinal fibers are exposed by hackling, and then, after deswelling, the fibers are cross-linked with hexamethylene diisocyanate in the presence of a nonionic or cationic emulsifier and are dehydrated and further processed on textile machines. .SIGMA.

390075

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