Method of making optically active alcohols

Details Method of making optically active alcohols Method of making optically active alcohols

C - Chemistry, Metallurgy

07

C

C07C 67/31 (2006.01) C07C 69/732 (2006.01) C07C 69/736 (2006.01) C07C 229/34 (2006.01) C07C 247/12 (2006.01) C07C 253/30 (2006.01) C07C 255/37 (2006.01) C07C 303/24 (2006.01) C07C 317/46 (2006.01) C07C 323/56 (2006.01) C07F 9/12 (2006.01)

Patent

CA 2050825

88/CCP36 18194 TITLE OF THE DISCLOSURE A METHOD OF MAKING OPTICALLY ACTIVE ALCOHOLS ABSTRACT OF TEE DISCLOSURE The present invention is directed to in-situ preparation of diisopinocamphenyl chloroborane, and the use of same in the reduction of prochiral ketones to optically active alcohols such as those of formula B. Image B The compound of Formula B is useful in the production 2,5-diaryltetrahydrofurans useful as PAF antagonists.

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