Method of manufacturing a therapeutic agent for the...

A - Human Necessities – 61 – K

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A61K 38/18 (2006.01)

Patent

CA 2214999

With the method of preparing a therapeutic agent for the treatment of multiple sclerosis, wherein human .beta. nerve growth factor (NGF) is brought into a pharmaceutically acceptable formulation for administering in a dose between 0.05 à 5 µg and 5 µg/kg body weight in 1 to 10 injections at an interval of 1 to 21 days, the regeneration of oligodendrocytes, especially for the treatment of multiple sclerosis, is improved and remyelination is accelerated.

Procédé de préparation d'un agent thérapeutique pour le traitement de la sclérose en plaques, dans lequel le facteur de croissance de tissu nerveux .beta. humain (NGF) est introduit dans une composition pharmaceutiquement acceptable. Ladite composition est destinée à être administrée à raison d'une dose de 0,05 µg/kg de poids corporel dans des injections effectuées à un intervalle de 1 à 21 jours. Ledit procédé permet d'améliorer la régénération des oligodendrocytes, en particulier pour le traitement de la sclérose en plaques, et une accélération de la remyélinisation.

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