A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 37/00 (2006.01) A61B 5/157 (2006.01) B81C 1/00 (2006.01)
Patent
CA 2436207
A method for manufacturing microneedle structures is disclosed using soft lithography and photolithography, in which micromold structures made of a photoresist material or PDMS are created. The micromold manufacturing occurs quite quickly, using inexpensive materials and processes. Once the molds are available, using moldable materials such as polymers, microneedle arrays can be molded or embossed in relatively fast procedures. In some cases a sacrificial layer is provided between the forming micromold and its substrate layer, for ease of separation. The microneedles themselves can be solid projections, hollow "microtubes," or shallow "microcups." Electrodes can be formed on the microneedle arrays, including individual electrodes per hollow microtube.
La présente invention concerne un procédé de fabrication de structures de microaiguilles au moyen de la lithographie douce et de la photolithographie, dans lequel on produit des structures de micro-moules en matériau de photorésine ou en PDMS. La fabrication de micro-moules s'effectue très rapidement, à l'aide de matériaux aptes au moulage tels que des polymères, des puces à injections peuvent être moulées ou estampées dans des processus relativement rapides. Dans certains cas une couche sacrificielle est prévue entre le micro-moule de formage et sa couche de support, permettant une séparation aisée. Les microaiguilles elles-mêmes peuvent constituer des projections pleines, des micro-tubes creux, ou des micro-cupules peu profondes. Les électrodes peuvent être formées sur les puces à injections, comprenant des électrodes individuelles par micro-tube creux.
Arias Francisco
Owens Grover David
Sherman Faiz Feisal
Battison Williams Dupuis
Corium International Inc.
The Procter & Gamble Company
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