Method of manufacturing solid dispersion

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/30 (2006.01) A61J 3/06 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2108575

The object of this invention is to provide a process for producing a solid dispersion, which has overcome the disadvantages of the conventional production technology for solid dispersions, The invention comprises employing a twin-screw extruder in the production of a solid dispersion. In accordance with the invention, a solid dispersion can be expediently produced without heating a drug and a polymer to or beyond their melting points and without using an organic solvent for dissolving both components and the resulting solid dispersion has excellent performance characteristics.

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