Method of modulating e-cadherin mediated cell adhesion

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) C07K 14/47 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2476965

The present invention relates to a method to modulate the E-cadherin mediated cell adhesion. More specifically, the invention relates to the use of hECRep1a and homologues thereof to modulate and/or control tumor cell invasiveness.

La présente invention concerne un procédé qui permet de moduler l'adhésion cellulaire à médiation par la E-cadhérine. En particulier, l'invention se rapporte à l'utilisation de hECRep1a et d'homologues de ce dernier dans le but de moduler et/ou enrayer le pouvoir envahissant des cellules tumorales.

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