Method of obtaining 2-(2-nitrovinyl)-furan and the use...

Details Method of obtaining 2-(2-nitrovinyl)-furan and the use... Method of obtaining 2-(2-nitrovinyl)-furan and the use...

C - Chemistry, Metallurgy

07

D

C07D 307/70 (2006.01) A61K 31/341 (2006.01) A61P 33/02 (2006.01)

Patent

CA 2466010

The invention relates to a method of obtaining and purifying 2-(2- nitrovinyl)furane consisting in reacting furfural and nitromethane, using isobutylamine as a catalyst and activated carbon as an adsorbent, in order to obtain a product of pharmaceutical quality. Said technique considerably reduces the environmental impact by eliminating the gaseous waste from the system by means of absorption in water. The inventive pharmaceutical composition contains 2-(2-nitrovinyl)furan and has powerful action against low concentrations of coccidia.

La présente invention concerne un procédé destiné à l'obtention et à la purification du 2-(2-nitrovinyl)furane, consistant à faire réagir du furfural et du nitrométhane en présence d'isobutylamine comme catalyseur et de charbon actif comme adsorbant, pour obtenir un produit de qualité pharmaceutique. Cette technique réduit sensiblement les effets sur l'environnement, car elle permet l'élimination par absorption dans l'eau des résidus gazeux du système. La composition pharmaceutique de la présente invention renferme du 2-(2-nitrovinyl)furane et présente une action puissance contre les coccidies en faibles concentrations.

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