Method of obtaining novel lutein-based formulations

A - Human Necessities – 61 – K

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A61K 9/16 (2006.01) A23L 1/275 (2006.01) A23L 1/30 (2006.01) A61K 8/34 (2006.01) A61K 8/67 (2006.01) A61K 8/73 (2006.01) A61K 8/92 (2006.01) A61K 31/047 (2006.01) A61K 47/22 (2006.01) A61K 47/36 (2006.01) A61K 47/44 (2006.01) A61P 3/02 (2006.01) A61J 3/00 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2471418

The invention relates to a method of preparing microcrystalline lutein formulations, particularly in the form of esters, which are oxidation stable and which are soluble in hydrophilic and lipophilic media. For this purpose, the lutein esters are mixed with antioxidants, vegetable oils and/or organic solvents, said initial mixture being subjected to various steps according to the type of formulation ultimately desired. Said formulations can be used directly as colouring agents as well as in the pharmaceutical, food and cosmetic fields. Moreover, the formulations can also be used as nutritional supplements.

La présente invention concerne un procédé de préparation de formulations de lutéine microcristalline, en particulier sous forme d'esters, stables à l'oxydation et solubles dans des milieux hydrophiles et/ou lipophiles. A cette fin, les esters de lutéine sont mélangés à des antioxydants, des huiles végétales et/ou des dissolvants organiques, ce mélange de départ étant soumis à diverses étapes en fonction du type de formulation que l'on souhaite finalement obtenir. Ces formulations sont utilisées directement comme colorants dans les domaines pharmaceutique, alimentaire et en cosmétique, et peuvent également être utilisées comme suppléments nutritionnels.

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